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Sponsors and Clinical Research Organizations

Why CHCRC and Community-Based Research Sites Are a Strategic Advantage for Pharma Sponsors and CRO Partners

Across the clinical research industry, sponsors and CROs are increasingly seeking faster activation timelines, reliable enrollment, operational consistency, and access to diverse patient populations. Yet the traditional site-by-site model often creates operational friction—multiple contracts, separate budgets, inconsistent start-up timelines, and uneven site performance.

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At Community Health Clinical Research Corporation (CHCRC), we are addressing these challenges by building a coordinated national network of Community Health Center research sites designed specifically to simplify how sponsors and CROs conduct clinical trials.

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Today, CHCRC has more than 30 active research sites, with additional centers joining through our 100-Site Pilot Program now underway. In the near future, our expansion strategy is expected to grow this network into hundreds of community-based research sites across the United States.

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For sponsors and CRO partners, this model delivers a fundamentally different experience.

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Instead of negotiating and managing dozens of independent sites, CHCRC provides a centralized Site Management Organization (SMO) structure that dramatically simplifies study start-up and operational oversight.

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Key advantages include:

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• One contract covering the entire network
• One budget structure rather than site-by-site negotiations
• Approval timelines measured in days rather than weeks or months
• Rapid site deployment through centralized operational infrastructure
• Central Institutional Review Board (IRB) oversight for consistent regulatory governance
• Central laboratory partnerships ensuring standardized specimen handling and biomarker analysis
• A unified Electronic Data Capture (EDC) platform for consistent data collection and reduced protocol deviations
• Standardized source documentation across participating sites
• Centralized training programs for investigators and clinical research coordinators
• Integrated regulatory and quality assurance oversight
• Remote, real-time monitoring capabilities across the entire network
• Single invoicing and payment structure simplifying sponsor financial management

Equally important is the patient population served by Community Health Centers.

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These centers care for millions of patients across urban, rural, and medically underserved communities—providing access to one of the most diverse and clinically relevant patient populations in the United States. As CHCRC expands its network, sponsors and CRO partners gain access to a rapidly growing, community-based research infrastructure capable of supporting large-scale enrollment and pragmatic clinical trials in real-world care settings.

Our mission goes beyond operational efficiency.

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CHCRC was built to redirect a portion of the private clinical research economy into America’s public healthcare safety-net, creating sustainable revenue streams for Community Health Centers while expanding patient access to innovative therapies and medical technologies.

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As our network continues to grow—from 30 sites today, to 100 sites in the near term, and hundreds in the years ahead—we believe CHCRC will become an essential partner for sponsors and CROs seeking efficient trial execution, reliable enrollment, and meaningful community engagement.

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The future of clinical research will not be confined to academic centers alone. It will be built within the communities where patients live, receive care, and place their trust in their healthcare providers. CHCRC is helping make that future possible.

Demographic Dossier

Breakdown of the 286,500 patients in CHCRCs clinical research infrastructure by age, sex, race, and health

Total Patient Reach: 286,500

Age Distribution

Racial Distribution

Chronic Disease Distribution

Under 18: 71,438 (25%)

18-64: 171,972 (60%)

65+: 43,090 (15%)

Hispanic: 155,163 (54%)

White: 64,299 (22%)

Black/African American: 46,336 (16%)

Asian: 3,657 (1-2%)

Other/Multiracial: 17,045 (6%)

Obesity: 111,038 (39%)

Hypercholesterolemia: 88,047 (31%)

Hypertension: 85,025 (30%)

Metabolic Syndrome: 76,019 (28%)

Chronic Pulmonary Disease: 61,492 (21%)

Type 2 Diabetes: 53,673 (19%)

Sex Distribution

Female:  164,422 (57%)

Male: 122,078 (42%)

Therapeutic Strengths 

Cardiovascular

Hypertension:

*85,025 patients (30%)

Age:

*18-65: 50,854 patients

*65+: 12,930 patients

Ethnicity:

*Hispanic: 45,091

*Black: 14,718

*White: 19,119

Heart Disease: 10,172 patients

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Strategic Impact: High density cardiometabolic burden enables efficient CVOT screening and enrollment

Obesity & Metabolic

Obesity:

*111,038 patients (39%)

Metabolic Syndrome:

*76,019 patients 

Hypercholesterolemia:

*88,047 patients

MASH:

*15,709 patients

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Strategic Impact: High Metabolic Clustering reduces screen failure in multi-indication protocols

Diabetes

Type 2 Diabetes:

*53,673 patients (~19%)

Age:

*18-64: 32,095

*65+: 8,063

Ethnicity:

*Hispanic: 29,202

*Black: 8,855

*White: 11,615

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Strategic Impact: Integrated Comorbidity Pipeline (Obesity > Diabetes > Hyperlipidemia > Cardiovascular Disease > MASH)

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Pulmonary

Total Chronic Pulmonary Burden:

*61,492 patients (21.5%)

Asthma:

*34,289 patients

*8,715 pediatric

COPD:

*15,303 patients

Chronic Bronchitis:

*11,900 patients

Strong Representation in Hispanic and Black populations

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Strategic Impact:

Ideal for:

*Biologic Asthma Trials

*Pediatric Inhaled Therapies

*COPD Maintenance Studies

Infectious Disease

HIV:

*1,923 patients

Hepatitis C:

*997 patients

Hepatitis B:

*444 patients

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Strategic Impact: Urban CHC representation supports long-acting injectable and antiviral protocols

Substance Use & Cross Disease Risk

Tobacco Use Disorder:

*13,246 patients

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Strategic Impact:

Critical Intersection with:

*Pulmonary Disease

*Oncology

*Cardiovascular Disease

Why Choose CHCRC over a Traditional
SMO?

01

Community-Embedded Collaboration in place of Academia-Centric Ideals

02

Primary Care Identification Employed vs. Recruitment Referrals

03

Highly Diverse Populations from Sites Nationwide vs. Homogenous Populations

04

Majority of Sites form Medical-Social Safety Net vs. Limited Medicaid Coverage in traditional SMOs

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Highly Secure, Centralized Oversight vs. Site-by-site variability

State-By-State Clinical Site
Demographic Breakdown

image from ultimaps.com

Last updated 03/12/26

🟢 ANNISTON, ALABAMA

Northeast Alabama Pediatrics

Total Active Patients: 17,000

Age Subtotals

  • Under 18 (30%): 5,100

  • 18–64 (55%): 9,350

  • 65+ (15%): 2,550

Ethnicity Subtotals

  • Black (48%): 8,160

  • White (42%): 7,140

  • Hispanic (5%): 850

  • Other (5%): 850

Diagnosis Subtotals

  • Hypertension (36%): 6,120

  • Type 2 Diabetes (22%): 3,740

  • Obesity (46%): 7,820

  • Metabolic Syndrome (28%): 4,760

  • MASH (6%): 1,020

  • Hypercholesterolemia (34%): 5,780

  • Thyroid Disorders (8%): 1,360

  • Chronic Bronchitis (7%): 1,190

  • COPD (10%): 1,700

  • Asthma (13%): 2,210

🟢 LOUISVILLE, KENTUCKY

Omni Resource Services

Total Active Patients: 10,000

Age Subtotals

  • Under 18: 2,200

  • 18–64: 6,000

  • 65+: 1,800

Ethnicity Subtotals

  • Black: 6,000

  • White: 3,000

  • Hispanic: 500

  • Other: 500

Diagnosis Subtotals

  • Hypertension: 3,200

  • Type 2 Diabetes: 1,900

  • Obesity: 4,100

  • Metabolic Syndrome: 2,500

  • MASH: 500

  • Hypercholesterolemia: 3,000

  • Thyroid: 700

  • Chronic Bronchitis: 600

  • COPD: 900

  • Asthma: 1,200

ultimaps-outlined-map-of-united-states-hq.png

🟢 BRONX, NEW YORK

Metro CHC – Bronx

Total Active Patients: 15,000

Age Subtotals

  • Under 18: 3,750

  • 18–64: 8,700

  • 65+: 2,550

Ethnicity Subtotals

  • Hispanic: 9,000

  • Black: 4,500

  • White: 750

  • Other: 750

Diagnosis Subtotals

  • Hypertension: 4,950

  • Type 2 Diabetes: 3,000

  • Obesity: 5,850

  • Metabolic Syndrome: 4,050

  • MASH: 750

  • Hypercholesterolemia: 4,650

  • Thyroid: 900

  • Chronic Bronchitis: 600

  • COPD: 900

  • Asthma: 2,100

🟢 MANHATTAN, NEW YORK

Metro CHC – Manhattan

Total Active Patients: 10,500

Age Subtotals

  • Under 18: 1,890

  • 18–64: 6,300

  • 65+: 2,310

Ethnicity Subtotals

  • Hispanic: 4,200

  • Black: 2,835

  • White: 2,415

  • Asian: 735

  • Other: 315

Diagnosis Subtotals

  • Hypertension: 3,045

  • Type 2 Diabetes: 1,785

  • Obesity: 3,570

  • Metabolic Syndrome: 2,415

  • MASH: 420

  • Hypercholesterolemia: 2,940

  • Thyroid: 735

  • Chronic Bronchitis: 315

  • COPD: 525

  • Asthma: 1,050

🟢 STATEN ISLAND, NEW YORK

Metro CHC – Staten Island

Total Active Patients: 11,500

Age Subtotals

  • Under 18: 2,300

  • 18–64: 6,555

  • 65+: 2,645

Ethnicity Subtotals

  • White: 4,600

  • Hispanic: 4,025

  • Black: 2,070

  • Other: 805

Diagnosis Subtotals

  • Hypertension: 3,565

  • Type 2 Diabetes: 2,070

  • Obesity: 4,370

  • Metabolic Syndrome: 2,990

  • MASH: 575

  • Hypercholesterolemia: 3,450

  • Thyroid: 805

  • Chronic Bronchitis: 575

  • COPD: 805

  • Asthma: 1,265

🟢 BROOKLYN, NEW YORK

Metro CHC – Downtown Brooklyn

Total Active Patients: 10,000

Age Subtotals

  • Under 18: 1,700

  • 18–64: 5,400

  • 65+: 2,900

Ethnicity Subtotals

  • Black: 4,500

  • Hispanic: 3,500

  • White: 1,500

  • Other: 500

Diagnosis Subtotals

  • Hypertension: 3,400

  • Type 2 Diabetes: 2,100

  • Obesity: 4,000

  • Metabolic Syndrome: 2,800

  • MASH: 600

  • Hypercholesterolemia: 3,200

  • Thyroid: 700

  • Chronic Bronchitis: 400

  • COPD: 600

  • Asthma: 1,200

🟢 MOUNT KISCO, NEW YORK

Open Door – 30 W Main St.

Total Active Patients: 10,500

Age Subtotals

  • Under 18 (23%): 2,415

  • 18–64 (63%): 6,615

  • 65+ (14%): 1,470

Ethnicity Subtotals

  • Hispanic (48%): 5,040

  • White (32%): 3,360

  • Black (12%): 1,260

  • Other (8%): 840

Diagnosis Subtotals

  • Hypertension (27%): 2,835

  • Type 2 Diabetes (14%): 1,470

  • Obesity (32%): 3,360

  • Metabolic Syndrome (22%): 2,310

  • MASH (4%): 420

  • Hypercholesterolemia (27%): 2,835

  • Thyroid Disorders (8%): 840

  • Chronic Bronchitis (3%): 315

  • COPD (5%): 525

  • Asthma (10%): 1,050

🟢 BREWSTER, NEW YORK

Open Door – 155 Main St.

Total Active Patients: 8,500

Age Subtotals

  • Under 18 (25%): 2,125

  • 18–64 (61%): 5,185

  • 65+ (14%): 1,190

Ethnicity Subtotals

  • Hispanic (46%): 3,910

  • White (35%): 2,975

  • Black (10%): 850

  • Other (9%): 765

Diagnosis Subtotals

  • Hypertension (26%): 2,210

  • Type 2 Diabetes (13%): 1,105

  • Obesity (31%): 2,635

  • Metabolic Syndrome (21%): 1,785

  • MASH (4%): 340

  • Hypercholesterolemia (26%): 2,210

  • Thyroid Disorders (7%): 595

  • Chronic Bronchitis (3%): 255

  • COPD (4%): 340

  • Asthma (11%): 935

🟢 OSSINING, NEW YORK

Open Door – 165 Main St.

Total Active Patients: 14,000

Age Subtotals

  • Under 18 (24%): 3,360

  • 18–64 (62%): 8,680

  • 65+ (14%): 1,960

Ethnicity Subtotals

  • Hispanic (52%): 7,280

  • White (28%): 3,920

  • Black (12%): 1,680

  • Other (8%): 1,120

Diagnosis Subtotals

  • Hypertension (28%): 3,920

  • Type 2 Diabetes (15%): 2,100

  • Obesity (34%): 4,760

  • Metabolic Syndrome (24%): 3,360

  • MASH (5%): 700

  • Hypercholesterolemia (29%): 4,060

  • Thyroid Disorders (7%): 980

  • Chronic Bronchitis (4%): 560

  • COPD (5%): 700

  • Asthma (11%): 1,540

🟢 SLEEPY HOLLOW, NEW YORK

Open Door – 300 N Broadway

Total Active Patients: 8,500

Age Subtotals

  • Under 18 (23%): 1,955

  • 18–64 (63%): 5,355

  • 65+ (14%): 1,190

Ethnicity Subtotals

  • Hispanic (50%): 4,250

  • White (30%): 2,550

  • Black (11%): 935

  • Other (9%): 765

Diagnosis Subtotals

  • Hypertension (27%): 2,295

  • Type 2 Diabetes (14%): 1,190

  • Obesity (33%): 2,805

  • Metabolic Syndrome (23%): 1,955

  • MASH (4%): 340

  • Hypercholesterolemia (27%): 2,295

  • Thyroid Disorders (7%): 595

  • Chronic Bronchitis (3%): 255

  • COPD (4%): 340

  • Asthma (10%): 850

🟢 PORT CHESTER, NEW YORK

Open Door – 5 Grace Church St.

Total Active Patients: 13,000

Age Subtotals

  • Under 18 (26%): 3,380

  • 18–64 (60%): 7,800

  • 65+ (14%): 1,820

Ethnicity Subtotals

  • Hispanic (58%): 7,540

  • White (25%): 3,250

  • Black (9%): 1,170

  • Other (8%): 1,040

Diagnosis Subtotals

  • Hypertension (29%): 3,770

  • Type 2 Diabetes (17%): 2,210

  • Obesity (36%): 4,680

  • Metabolic Syndrome (26%): 3,380

  • MASH (5%): 650

  • Hypercholesterolemia (30%): 3,900

  • Thyroid Disorders (6%): 780

  • Chronic Bronchitis (4%): 520

  • COPD (4%): 520

  • Asthma (13%): 1,690

🟢 MAMARONECK, NEW YORK

Open Door – 689 Mamaroneck Ave

Total Active Patients: 8,500

Age Subtotals

  • Under 18 (22%): 1,870

  • 18–64 (64%): 5,440

  • 65+ (14%): 1,190

Ethnicity Subtotals

  • Hispanic (44%): 3,740

  • White (38%): 3,230

  • Black (10%): 850

  • Other (8%): 680

Diagnosis Subtotals

  • Hypertension (25%): 2,125

  • Type 2 Diabetes (13%): 1,105

  • Obesity (30%): 2,550

  • Metabolic Syndrome (20%): 1,700

  • MASH (4%): 340

  • Hypercholesterolemia (25%): 2,125

  • Thyroid Disorders (8%): 680

  • Chronic Bronchitis (3%): 255

  • COPD (4%): 340

  • Asthma (10%): 850

🟢 CORONA, CALIFORNIA

Centro Medico – 1303 W 6th St., Corona, CA 92882

Total Active Patients: 12,000

Age Subtotals

  • Under 18 (28%): 3,360

  • 18–64 (60%): 7,200

  • 65+ (12%): 1,440

Ethnicity Subtotals

  • Hispanic (75%): 9,000

  • White (12%): 1,440

  • Black (5%): 600

  • Other (8%): 960

Diagnosis Subtotals

  • Hypertension (28%): 3,360

  • Type 2 Diabetes (20%): 2,400

  • Obesity (39%): 4,680

  • Metabolic Syndrome (27%): 3,240

  • MASH (6%): 720

  • Hypercholesterolemia (31%): 3,720

  • Thyroid Disorders (6%): 720

  • Chronic Bronchitis (4%): 480

  • COPD (5%): 600

  • Asthma (12%): 1,440

🟢 LOS ANGELES, CALIFORNIA

Centro Medico – Vernon Ave

231 W Vernon Ave #203, Los Angeles, CA 90037
Total Active Patients: 15,000

Age Subtotals

  • Under 18 (26%): 3,900

  • 18–64 (61%): 9,150

  • 65+ (13%): 1,950

Ethnicity Subtotals

  • Hispanic (80%): 12,000

  • Black (8%): 1,200

  • White (7%): 1,050

  • Other (5%): 750

Diagnosis Subtotals

  • Hypertension (29%): 4,350

  • Type 2 Diabetes (21%): 3,150

  • Obesity (41%): 6,150

  • Metabolic Syndrome (29%): 4,350

  • MASH (6%): 900

  • Hypercholesterolemia (33%): 4,950

  • Thyroid Disorders (6%): 900

  • Chronic Bronchitis (4%): 600

  • COPD (4%): 600

  • Asthma (13%): 1,950

🟢 LOS ANGELES, CALIFORNIA

Centro Medico – Santa Rosalia

3762 Santa Rosalia Dr., Los Angeles, CA 90008
Total Active Patients: 11,000

Age Subtotals

  • Under 18 (26%): 2,860

  • 18–64 (61%): 6,710

  • 65+ (13%): 1,430

Ethnicity Subtotals

  • Hispanic (80%): 8,800

  • Black (8%): 880

  • White (7%): 770

  • Other (5%): 550

Diagnosis Subtotals

  • Hypertension (29%): 3,190

  • Type 2 Diabetes (21%): 2,310

  • Obesity (41%): 4,510

  • Metabolic Syndrome (28%): 3,080

  • MASH (6%): 660

  • Hypercholesterolemia (32%): 3,520

  • Thyroid Disorders (6%): 660

  • Chronic Bronchitis (4%): 440

  • COPD (4%): 440

  • Asthma (12%): 1,320

🟢 SAN DIEGO, CALIFORNIA

Nestor Community Health Center – 1016 Outer Rd., San Diego, CA 92154

Total Active Patients: 13,000

Age Subtotals

  • Under 18 (26%): 3,380

  • 18–64 (62%): 8,060

  • 65+ (12%): 1,560

Ethnicity Subtotals

  • Hispanic (73%): 9,490

  • White (20%): 2,600

  • Black (3%): 390

  • Other (4%): 520

Diagnosis Subtotals

  • Hypertension (27%): 3,510

  • Type 2 Diabetes (18%): 2,340

  • Obesity (38%): 4,940

  • Metabolic Syndrome (26%): 3,380

  • MASH (6%): 780

  • Hypercholesterolemia (30%): 3,900

  • Thyroid Disorders (6%): 780

  • Chronic Bronchitis (4%): 520

  • COPD (4%): 520

  • Asthma (12%): 1,560

CHCRC Network Oncology Trial Feasibility by Site

Estimated Patient Pools for Five Common Oncology Indications

Site                                                          Patient Pop.         Breast          Prostate       Colorectal       Lung       Cervical            Total

Metro CHC – Bronx                             11250                    146               135                 90                    45              23                    439
Metro CHC – Manhattan                    8610                     112                103                69                     34             17                      335
Metro CHC – Downtown Brooklyn  8300                     108                100               66                     33             17                      324
Metro CHC – Staten Island               9200                     120                110                 74                     37             18                      359
Open Door – Ossining                        10640                   138                128                 85                     43             21                       415
Open Door – Port Chester                 9620                     125                115                  77                      38            19                       374
Open Door – Mount Kisco                8085                      105                 97                 65                      32            16                       315
Open Door – Brewster                       6375                       83                  77                  51                      26            13                       250
Open Door – Sleepy Hollow             6545                       85                  79                  52                     26            13                       255
Open Door – Mamaroneck               6630                      86                  80                  53                     27             13                       259
Centro Medico – Los Angeles          11100                     144                133                 89                     44             22                      432
Centro Medico – Corona                   8640                      112                104                69                     35             17                       337
Imperial Beach Clinic                        11400                     148                137                91                      46            23                       445
Nestor CHC – San Diego                   9620                      125                115                 77                     38            19                       374
Castle FH – Atwater (3605)             9585                       125                115                 77                     38            19                       374
Castle FH – Atwater (1775)              8165                       106                98                  65                     33            16                       318
Castle FH – Winton                           6300                      82                  76                  50                     25            13                       246
Omni Resource – Louisville             7800                     101                 94                  62                     31             16                       304
Wright Center – Scranton                9500                     124                114                  76                     38            19                        371
Anniston CHC – Alabama               11900                     155                143                 95                     48             24                      465

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